abstract：BACKGROUND:Increased, decreased, as well as unchanged pituitary volumes have been reported in bipolar disorders (BD). It is unclear, whether abnormal pituitary volumes increase vulnerability for BD (primary vulnerability marker), or are secondary to burden of illness. To address this question, we performed the first hi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hajek T,Gunde E,Bernier D,Slaney C,Propper L,Macqueen G,Duffy A,Alda M

更新日期：2008-09-01 00:00:00

abstract：:This study aims to investigate the relationship between regional connectivity in the brain white matter and the presence of psychotic personality traits, in healthy subjects with psychotic traits. Thirteen healthy controls were administered the MMPI-2, to assess psychotic traits and, according to MMPI results, a dicho...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Volpe U,Federspiel A,Mucci A,Dierks T,Frank A,Wahlund LO,Galderisi S,Maj M

更新日期：2008-08-01 00:00:00

abstract：:This article systematically reviews the literature on the outcome of acute hospitalization for adult general psychiatric patients admitted involuntarily as compared to patients admitted voluntarily. Inclusion and exclusion criteria qualified 41 out of 3,227 references found in Medline and PSYNDEXplus literature search...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kallert TW,Glöckner M,Schützwohl M

更新日期：2008-06-01 00:00:00

abstract：:Emil Kraepelin is well known due to his development of the psychiatric classification. The ICD-10 and DSM-IV classification is based on the dichotomy of endogenous psychoses into affective psychoses and schizophrenia as early as 1899. Moreover, beside his classification system he put enormous impact on the development...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Hippius H,Müller N

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:We tested Kraepelin's dichotomy model by studying the separability of schizophrenia and depression on the basis of symptoms and illness course. MATERIALS AND METHODS:Matched untreated patients with schizophrenia and depression (n = 130 each) and 130 "healthy" controls were assessed from onset to first admiss...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,an der Heiden W,Maurer K

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:Mental health is one of the priorities of the European Commission. Studies of the use and cost of mental health facilities are needed in order to improve the planning and efficiey of mental health resources. We analyze the patterns of mental health service use in multiple clinical settings to identify factors a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Baca-Garcia E,Perez-Rodriguez MM,Basurte-Villamor I,Quintero-Gutierrez FJ,Sevilla-Vicente J,Martinez-Vigo M,Artes-Rodriguez A,Fernandez del Moral AL,Jimenez-Arriero MA,Gonzalez de Rivera JL

更新日期：2008-03-01 00:00:00

abstract：:The purpose of this article is to encourage research investigating the role of measured gene-environment interaction (G x E) in the etiology of posttraumatic stress disorder (PTSD). PTSD is uniquely suited to the study of G x E as the diagnosis requires exposure to a potentially-traumatic life event. PTSD is also mode...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Koenen KC,Nugent NR,Amstadter AB

更新日期：2008-03-01 00:00:00

abstract：:Based on the original data from two double-blind, randomized, placebo-controlled clinical trials and the acute phase of a long-term study that investigated the antidepressant efficacy of St. John's wort extract WS 5570, we present a re-analysis of a subset of patients suffering from an acute episode of mild depression...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Kasper S,Gastpar M,Müller WE,Volz HP,Dienel A,Kieser M,Möller HJ

更新日期：2008-02-01 00:00:00

abstract：:Neurofunctional mechanisms underlying cognitive behavior therapy (CBT) are still not clearly understood. This functional magnetic resonance imaging (fMRI) study focused on changes in brain activation as a result of one-session CBT in patients suffering from spider phobia. Twenty-six female spider phobics and 25 non-ph...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schienle A,Schäfer A,Hermann A,Rohrmann S,Vaitl D

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Only few studies have investigated executive impairment in the euthymic phase of unipolar affective disorders, yielding diverging results. The role of impulsivity/orbitofrontal associated executive functioning in remitted depression has not yet been examined. METHODS:Partly remitted male out-patients (n = 1...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Westheide J,Wagner M,Quednow BB,Hoppe C,Cooper-Mahkorn D,Strater B,Maier W,Kuhn KU

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:This exploratory study aims to compare lifetime psychiatric axis-I-comorbidity and psychosocial functioning in a clinically referred sample of adult patients with attention-deficit/hyperactivity disorder (ADHD) with a population-based healthy control group and to examine whether patients with ADHD and lifetim...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Sobanski E,Brüggemann D,Alm B,Kern S,Deschner M,Schubert T,Philipsen A,Rietschel M

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The prevalence and consequences of co-morbid axis-I and axis-II disorders as well as personality traits were examined in a large cohort of adult attention-deficit/hyperactivity disorder (AADHD) at a tertiary referral center. METHODS:In- and outpatients referred for diagnostic assessment of AADHD were screene...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Jacob CP,Romanos J,Dempfle A,Heine M,Windemuth-Kieselbach C,Kruse A,Reif A,Walitza S,Romanos M,Strobel A,Brocke B,Schäfer H,Schmidtke A,Böning J,Lesch KP

更新日期：2007-09-01 00:00:00

abstract：:Germany turned towards community-based mental health care in the mid seventies, during a general climate of social and political reform. The continuing deinstitutionalisation process and the implementation of community mental health services was considerably affected by the reunification of East and West Germany in 19...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Salize HJ,Rössler W,Becker T

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:Patients with somatoform pain often complain of sleep disorders, but sleep disorders are not an integrated part of the diagnosis of this disorder. Restless legs syndrome is associated with painful symptoms and sleep disturbances. The aim of our study was to evaluate the prevalence of restless legs syndrome (...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Aigner M,Prause W,Freidl M,Weiss M,Izadi S,Bach M,Saletu B

更新日期：2007-02-01 00:00:00

abstract：:The ability of humans to predict and explain other people's behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a "Theory of Mind". Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critic...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Mazza M,Costagliola C,Di Michele V,Magliani V,Pollice R,Ricci A,Di Giovanbattista E,Roncone R,Casacchia M,Galzio RJ

更新日期：2007-02-01 00:00:00

abstract：:To assess the course of neuropsychological (NP) impairment in schizophrenia, 71 patients with first episode (FE) schizophrenia and 71 healthy controls were given a comprehensive battery of NP tests at index assessment, after a 2-year and after a 5-year follow-up period. By means of the z-score standardization, summary...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albus M,Hubmann W,Mohr F,Hecht S,Hinterberger-Weber P,Seitz NN,Küchenhoff H

更新日期：2006-10-01 00:00:00

abstract：:Studies addressing the relationship between a history of obstetric complications (OCs) and neurological abnormalities in schizophrenia have produced contradictory findings. Using a pre-posttreatment design in a neuroleptic-naive sample of psychotic patients, we examined the relationship of a history of OC to primary a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Peralta V,Cuesta MJ,Serrano JF

更新日期：2006-10-01 00:00:00

abstract：:In this review, we discuss current structural and functional imaging data on ADHD in a neurological and neuroanatomical framework. At present, the literature on adult ADHD is somewhat sparse, and so results from imaging have to therefore be considered mainly from the childhood or adolescence perspective. Most work has...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Schneider M,Retz W,Coogan A,Thome J,Rösler M

更新日期：2006-09-01 00:00:00

abstract：AIM:This study examined the extent to which fathers' and infants' interaction behavior were related to children's externalizing behavior problems at age 8 and 11 years. METHODS:In a prospective longitudinal study of children at risk for later psychopathology, 72 fathers and their 3-month-old children were videotaped a...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Trautmann-Villalba P,Gschwendt M,Schmidt MH,Laucht M

更新日期：2006-09-01 00:00:00

abstract：:The aim of the study was to evaluate the relationship between social problem solving ability, clinical features and cognitive functions, and determine the predictors of benefit from social problem solving training in 63 patients with schizophrenia. We administered Brief Psychiatric Rating Scale (BPRS), Wisconsin Card ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Uçok A,Cakir S,Duman ZC,Dişcigil A,Kandemir P,Atli H

更新日期：2006-09-01 00:00:00

abstract：:The aim of this study was to investigate theory of mind (ToM) ability in patients in remission after the first episode of schizophrenia. A ToM task which contained four pictures was given to 30 patients with schizophrenia in remission and 30 matched healthy controls. Patients with schizophrenia in remission showed sta...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Inoue Y,Yamada K,Hirano M,Shinohara M,Tamaoki T,Iguchi H,Tonooka Y,Kanba S

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:The aims of this study are threefold: to depict characteristics of homeless at discharge from a psychiatric hospital; to describe the utilisation of inpatient care and treatment measures during hospitalisation; and to analyse to what extent psychiatric disorders and clinical variables contribute to the risk f...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Lauber C,Lay B,Rössler W

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Several predictors of Alzheimer's disease (AD) have been identified. However, the relevance and independent contribution of risk factors and of possible early signs such as mild cognitive impairment and subjective memory impairment on the development of AD has not been investigated prospectively in a cohort o...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Heun R,Kölsch H,Jessen F

更新日期：2006-02-01 00:00:00

abstract：:Anger is a common and potentially destructive emotion that has considerable social and public health importance. The occurrence of anger, irritability and hostility in depression have been known for many years, but the prevalence, significance for treatment and prognosis and the mechanisms involved remain poorly under...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Painuly N,Sharan P,Mattoo SK

更新日期：2005-08-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL), a rare type of non-Hodgkin's lymphoma, is an uncommon cause of progressive dementia, usually followed by death within a few months of onset of clinical disease. Often this aggressive tumor is only diagnosed at autopsy, because of misleading clinical features mimicking a broad spectru...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Albrecht R,Krebs B,Reusche E,Nagel M,Lencer R,Kretzschmar HA

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Risk factors, emergence and accumulation of symptoms in the untreated early course were studied as a basis for understanding the relationship between schizophrenia and depression. MATERIALS AND METHODS:130 representative first admissions for schizophrenia were compared retrospectively with 130 individually m...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Häfner H,Maurer K,Trendler G,an der Heiden W,Schmidt M

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Interpersonal psychotherapy (IPT) is a time-limited psychotherapy for major depression. The aim of this study is to summarize findings from controlled trials of the efficacy of IPT in the treatment of depressive spectrum disorders (DSD) using a meta-analytic approach. METHODS:Studies of randomized clinical t...

journal_title：European archives of psychiatry and clinical neuroscience

authors： de Mello MF,de Jesus Mari J,Bacaltchuk J,Verdeli H,Neugebauer R

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:The present study aims to assess the factor structure of the DSM-IV Premenstrual Dysphoric Disorder (PMDD) symptoms and its relationship with depressive symptoms. METHODS:We evaluated retrospectively PMDD symptoms in 513 female college students, through a self-reporting questionnaire based on DSM-IV criteri...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Teng CT,Filho AH,Artes R,Gorenstein C,Andrade LH,Wang YP

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Childhood traumatic experiences, rearing styles, familial mental disorders and birth risk factors have been associated with the development of social anxiety disorder. METHOD:Patients with social anxiety disorder (n=50) and healthy controls (n=120) were investigated using a retrospective interview with 203 q...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Bandelow B,Charimo Torrente A,Wedekind D,Broocks A,Hajak G,Rüther E

更新日期：2004-12-01 00:00:00

abstract：:This study investigates the nosological specificity and time stability of reduced facial expressivity in schizophrenia by means of objective measurement. Facial expression in an emotional interview was evaluated using the "Facial Action Coding System" in 33 acute schizophrenia patients and 23 acute depressive patients...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gaebel W,Wölwer W

更新日期：2004-10-01 00:00:00

abstract：:Sustainable observations suggest that suicidal behaviour by itself may have biological correlates, among which those related to the serotonergic synapse hold the key position. Based on the association of suicide and serotonergic dysfunction, it was proposed that genetic mechanisms affecting suicidal behaviour could be...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Stefulj J,Büttner A,Kubat M,Zill P,Balija M,Eisenmenger W,Bondy B,Jernej B

更新日期：2004-08-01 00:00:00

abstract：:The deficit syndrome is thought to be specific to and a subtype of schizophrenia; however, there are scarce or no data on the prevalence and characteristics of this syndrome in non-schizophrenic psychoses. The aim of this study was to explore the prevalence and correlates of different types of negative symptoms (NegS)...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Peralta V,Cuesta MJ

更新日期：2004-06-01 00:00:00

abstract：:The novel/atypical neuroleptics have proven to be effective in treating negative symptoms but although clinical experience appears to show that they have advantages over the traditional neuroleptics in treating negative symptoms, superiority has not always been statistically confirmed and the treatment results in indi...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Möller HJ

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:Fluoxetine and its active metabolite norfluoxetine have long half-lives. We postulate that, owing to the long elimination half-life and the time to reach steady-state level in plasma is nearly four weeks, patients diagnosed with major depressive disorder might be treated with fluoxetine taken once every third...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tural U,Onder E

更新日期：2003-12-01 00:00:00

abstract：:The aim of this study was to reexamine and compare the characteristics of the deficit and nondeficit schizophrenic patients. This cross-sectional study consisted of 62 in- and out-patients, 18-65 years of age, diagnosed with schizophrenia according to DSM-IV. The sociodemographic variables, premorbid adjustment, clini...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Tiryaki A,Yazici MK,Anil AE,Kabakçi E,Karaağaoğlu E,Göğüş A

更新日期：2003-10-01 00:00:00

abstract：:There are gender-related differences in the prevalence, course and treatment response characteristics of schizophrenia and mood disorders. Gonadal steroids exert potent effects on mood, cognition and behavior, and there is little doubt that androgens are crucial for differentiating to each gender. Serum level of total...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Ozcan ME,Banoglu R

更新日期：2003-08-01 00:00:00

abstract：:P300 is an event-related potential that is elicited by an oddball paradigm. In several neuropsychiatric diseases, differences in latencies and amplitude compared to healthy subjects have been reported. Because of its clinical significance, several investigations have tried to elucidate the intracranial origins of the ...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Horn H,Syed N,Lanfermann H,Maurer K,Dierks T

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:This placebo-controlled study was designed to investigate the influence of two different stimulation procedures of repetitive transcranial magnetic stimulation (rTMS) on depressive symptoms in patients with depressive disorders. Furthermore, effects on cognitive functions and psychomotor functioning were tes...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Höppner J,Schulz M,Irmisch G,Mau R,Schläfke D,Richter J

更新日期：2003-04-01 00:00:00

abstract：:Dopamine D(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. In recent years atypical antipsychotics such as olanzapine, which have high serotonin 5-HT(2A)/dopamine D(2) occupation ratios, have been...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Gonul AS,Kula M,Sofuoglu S,Tutus A,Esel E

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:While there is ample evidence that the prevalence rates for major depressive disorder (MDD) in the general population are higher in women than in men, there is little data on gender differences as regard to symptoms, causal attribution, help-seeking, coping, or the consequences of depression. METHOD:The lar...

journal_title：European archives of psychiatry and clinical neuroscience

authors： Angst J,Gamma A,Gastpar M,Lépine JP,Mendlewicz J,Tylee A,Depression Research in European Society Study.

更新日期：2002-10-01 00:00:00